Welcome to the Tao Liu Lab at Roswell Park Comprehensive Cancer Center.
We develop computational methods and open-source software to study transcriptional and epigenetic regulation, with a focus on cancer biology, single-cell genomics, and AI-enabled genomics data reuse.
Research at a glance
- Algorithm development for ChIP-seq, CUT&RUN, ATAC-seq, and single-cell assays
- Regulatory genomics in cancer and developmental systems
- AI agent development for genomics data reuse and metadata standardization
- Scalable, reproducible analysis workflows and data infrastructure
Quick links
Latest News
- Software Release: coala framework for turning command-line tools into agentic toolsets (2026-02-25)
- Review by AI: Biological Information Storage and Flow (2026-02-23)
- Publication: Computational analyses and challenges of single-cell ATAC-seq (2025-11-21)
- Publication: Disrupting AR-WDR77 interaction delays treatment-resistant prostate cancer growth (2025-09-09)
Featured Software
Join / Contact
We welcome collaborations and applications from students and postdocs interested in computational biology, gene regulation, single-cell genomics, and AI for biomedical data analysis.
- Contact: tao.liu@roswellpark.org
- Lab overview: Research